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Understanding cellular heterogeneity in pancreatic cancer

November 27, 2018 @ 6:00 pm - 8:00 pm

This event is held in the Pfizer lecture theatre in the Cambridge University Chemistry Department and will be followed with a wine and cheese reception.

“Every organ harbours adult stem cells which have the potential for long-term replication, together with the capacities of self-renewal and multi-lineage differentiation. These stem cells function in tissue homeostasis and contribute to regeneration in response to injury. In addition, many cancers are caused by transforming mutations occurring in tissue-specific progenitor cells. Moreover, tumours are also organised in a cellular hierarchy, with the so-called cancer stem cells being at the apex. Dr Behrens’ major aim is to elucidate the molecular mechanisms governing stem cell functions in the context of tumour development. Recent results will be discussed.
Dr Behrens has a long-standing interest in cell signalling pathways that control cell fate. During his PhD at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria and subsequent postdoctoral work in Switzerland, he developed animal models of cancer and neurodegeneration. Building on this expertise in mouse models of human diseases, Dr Behrens set up his laboratory at the Cancer Research UK London Research Institute in 2001, now part of the Francis Crick Institute, and has since focused on the function of stem cells in tissue homeostasis and cancer and, more recently, in diabetes. He has also been a Principal Fellow at Kings College London since 2013.”


November 27, 2018
6:00 pm - 8:00 pm


Dr Axel Behrens


Department of Chemistry
Lensfield Rd
Cambridge, CB2 1EW United Kingdom
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